Sustained metabolic scope.

The metabolic integrity of hepatocytes in sustained incubations.

Over the past few years, suspensions of isolated hepatocytes have become accepted as important systems for studying hepatic metabolism and its control [ 1) . Several methods that yield hepatocyte suspensions physiologically similar to intact liver have been published [2-41 . Although this similarity is apparent immediately after isolation, incubation of hepatocytes at 37°C in simple salt soluti...

Chronic neutral phosphate supplementation induces sustained, renal metabolic alkalosis.

The aim of the present study was to test whether intravenous neutral phosphate supplementation, recently shown in our laboratory to acutely stimulate proton secretion in the distal nephron, was able to induce a sustained metabolic alkalosis. Neutral Na and K phosphate supplementation for seven days, with equivalent reduction in chloride supply and unchanged intake of sodium and potassium, in AD...

The Scope of Man's Free Will

Immune-Challenged Fish Up-Regulate Their Metabolic Scope to Support Locomotion

Energy-based trade-offs occur when investment in one fitness-related trait diverts energy away from other traits. The extent to which such trade-offs are shaped by limits on the rate of conversion of energy ingested in food (e.g. carbohydrates) into chemical energy (ATP) by oxidative metabolism rather than by the amount of food ingested in the first place is, however, unclear. Here we tested wh...

The Draft Genome Sequence of Nocardioides sp. Strain CF8 Reveals the Scope of Its Metabolic Capabilities

Nocardioides sp. strain CF8 was isolated from a soil sample collected at the Hanford Department of Energy site, Richland, WA. The strain was identified in microcosms based on its ability to grow on butane and has been characterized for its potential applications in the biodegradation of halogenated hydrocarbons. Here, the draft genome sequence is reported.